Listed below are the current guidelines, provisional clinical opinions, endorsements, and updates in development. Topics prioritized for development by the Clinical Practice Guidelines Committee and Guideline Advisory Groups are listed by disease site. To submit a topic for consideration, take our survey. To learn more about the ASCO Guideline development process, access the Guideline Methodology page.

Guidelines/Provisional Clinical Opinions (PCOs)/Endorsements in Development

Breast Cancer

  • Management of the Axilla in Early-Stage Breast Cancer
  • Neoadjuvant Therapy for Breast Cancer
  • Endocrine Therapy for Hormone Receptor–Positive Metastatic Breast Cancer
  • Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer. 
  • CCO-ASCO Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer 
  • Update: Systemic Therapy for Patients With Advanced HER2–Positive Breast Cancer
  • Update: Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases
  • Update: Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer
  • Update: Chemo- and Targeted Therapy for Women with HER2 Negative (or unknown) Advanced Breast Cancer

Gastrointestinal Cancer

  • Adjuvant Therapy for Stage II Colon Cancer
  • Advanced Colon Cancer 

Genitourinary Cancer​

  • Management of Metastatic Renal Clear Cell Cancer
  • EAU-ASCO Joint Penile Cancer Guideline 
  • Update: Initial Management of Non-Castrate Metastatic, Recurrent, or Progressive Prostate Cancer

Head and Neck Cancer

  • Management of Salivary Gland Malignancy

Neurooncology

  • Treatment of Patients with Brain Metastases
  • Therapy for Diffuse Astrocytic and Oligodendroglial Tumors

Resource Stratified​

  • Assessment of Adult Women with Ovarian Masses and Treatment of Epithelial Ovarian Cancer
  • Update: Cervical Cancer Secondary Prevention Resource-Stratified Guideline  

Supportive Care

Survivorship

Thoracic

  • Management of Stage III NSCLC
  • Radiation Therapy for SCLC
  • Update: Therapy for Stage IV Non–Small-Cell Lung Cancer with Driver Alterations Update

Multi-Site

  • Somatic Genomic Panel Testing for Metastatic Disease
  • Treatment for Brain Metastases 
  • Therapy for Diffuse Astrocytic and Oligodendroglial Tumors 

Guideline Priorities 2020-2021

Breast Cancer

  • Local Management Of De Novo Metastatic Breast Cancer
  • Germline Mutation Testing Among Women with A Personal History of Breast Cancer
  • Adjuvant Endocrine Therapy for Women with Hormone Receptor-Positive Breast Cancer
  • Management of Older-Age Breast Cancer Patients with Early-Stage Breast Cancer
  • Management of Breast Cancer in Pregnant Patients

Gastrointestinal Cancer

  • Immunotherapy for Gastroesophageal Cancers 
  • Targeted Therapy for Biliary Cancers 
  • Systemic Therapy for Advanced Neuroendocrine Cancer
  • Perioperative Management of Gastric Cancer 
  • Neoadjuvant and Adjuvant Therapy for Rectal Cancer, Including Watchful Waiting 

Genitourinary Cancer​

  • Genomic and Germline Testing in Local and Advanced Prostate Cancer 
  • Genitourinary Cancers Survivorship
  • Special Considerations for Elderly Patients with Genitourinary Cancers
  • Endorsement of Appropriate Use Criteria for Imaging Evaluation of Biochemical Recurrence of Prostate Cancer After Definitive Primary Treatment
  • Update: Systemic Therapy in Men with Metastatic Castration-Resistant Prostate Cancer

Gynecologic Cancer

Head and Neck Cancer

  • Use of Immune Checkpoint Inhibitors and PD-L1 Testing in Head and Neck Squamous Cell Carcinoma, Focusing on Recurrent/Metastatic Disease
  • Transoral Robotic Surgery and Multidisciplinary Care of Oropharynx Cancer: Pre-op Decision-Making, Post-Op Treatment
  • Consideration of Dental Care and Osteonecrosis in Patients Treated with Radiotherapy for Head and Neck Cancer
  • Management of Locoregionally Recurrent Head and Neck Cancer Including Re-Irradiation
  • Use of Systemic Treatment in the Management of Advanced Thyroid Cancer

Multi-Site

  • Germline Genetic Testing
  • Recommendations Regarding the Testing of Tumor-Agnostic Markers and Offering Associated Therapies
  • Management of Leptomeningeal Disease 
  • Use of cfDNA in Diagnosis and Monitoring in Solid Tumors As Well As Lymphomas

Resource Stratified

  • Update: Chemo- and Targeted Therapy for Patients with Triple-Negative, HER2+, or ER+ and Endocrine Resistant Metastatic Breast Cancer
  • Update: Endocrine Therapy for ER+/PR+ Metastatic Breast Cancer 
  • Update: Survivorship Care in Adolescents, Young Adults, and Adults
  • Update: Treatment of Patients with Endometrial Cancer
  • Update: Geriatric Oncology

Supportive Care

  • Prognostic Communication and Advance Care Planning 
  • ​Medical Cannabis in Cancer Symptom Care
  • Integration of Palliative Care into Standard Oncology Care Update
  • Management of Financial Toxicity of Cancer and its Treatment 
  • Management of Dermatologic Events to Cancer Therapies

Survivorship

  • YA Survivorship for Ages 21-39
  • Management of Sleep Problems in Cancer Survivors
  • Exercise, Weight, and Obesity in Post-Treatment Cancer Survivors
  • Survivorship After Stem Cell Transplantation
  • Survivorship for Metastatic (Non-Hematological) Cancer

Thoracic

  • Systemic Therapy for Resectable EGFR Positive NSCLC
  • Systemic Therapy for Small Cell Lung Cancer
  • Management of Oligometastasis and Oligoprogressive Disease

Recently Published Guidelines