Listed below are the current guidelines, provisional clinical opinions, endorsements, and updates in development. Topics prioritized for development by the Clinical Practice Guidelines Committee and Guideline Advisory Groups are listed by disease site. To submit a topic for consideration, take our survey. To learn more about the ASCO Guideline development process, access the Guideline Methodology page.
Guidelines/Provisional Clinical Opinions (PCOs)/Endorsements in Development
Breast Cancer
- Management of the Axilla in Early-Stage Breast Cancer
- Neoadjuvant Therapy for Breast Cancer
- Endocrine Therapy for Hormone Receptor–Positive Metastatic Breast Cancer
- Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer.
- CCO-ASCO Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer
- Update: Systemic Therapy for Patients With Advanced HER2–Positive Breast Cancer
- Update: Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases
- Update: Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer
- Update: Chemo- and Targeted Therapy for Women with HER2 Negative (or unknown) Advanced Breast Cancer
Gastrointestinal Cancer
- Adjuvant Therapy for Stage II Colon Cancer
- Advanced Colon Cancer
Genitourinary Cancer
- Management of Metastatic Renal Clear Cell Cancer
- EAU-ASCO Joint Penile Cancer Guideline
- Update: Initial Management of Non-Castrate Metastatic, Recurrent, or Progressive Prostate Cancer
Head and Neck Cancer
- Management of Salivary Gland Malignancy
Neurooncology
- Treatment of Patients with Brain Metastases
- Therapy for Diffuse Astrocytic and Oligodendroglial Tumors
Resource Stratified
- Assessment of Adult Women with Ovarian Masses and Treatment of Epithelial Ovarian Cancer
- Update: Cervical Cancer Secondary Prevention Resource-Stratified Guideline
Supportive Care
- Management of Dyspnea in Advanced Cancer
- Salivary Gland Hypofunction and/or Xerostomia Induced by Non-Surgical Cancer Therapies: ISOO/MASCC/ASCO Clinical Practice Guideline
- Diet, Physical Activity, and Weight Management During Cancer Treatment
- Use of Opioids During Cancer Treatment
- Update: Appropriate Chemotherapy Dosing for Obese Adult Patients With Cancer
- Update: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy
Survivorship
- Update: Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer Guideline Adaptation
- Update: Screening, Assessment, and Care of Anxiety and Depressive Symptoms in Adults With Cancer Guideline Adaptation
Thoracic
- Management of Stage III NSCLC
- Radiation Therapy for SCLC
- Update: Therapy for Stage IV Non–Small-Cell Lung Cancer with Driver Alterations Update
Multi-Site
- Somatic Genomic Panel Testing for Metastatic Disease
- Treatment for Brain Metastases
- Therapy for Diffuse Astrocytic and Oligodendroglial Tumors
Guideline Priorities 2020-2021
Breast Cancer
- Local Management Of De Novo Metastatic Breast Cancer
- Germline Mutation Testing Among Women with A Personal History of Breast Cancer
- Adjuvant Endocrine Therapy for Women with Hormone Receptor-Positive Breast Cancer
- Management of Older-Age Breast Cancer Patients with Early-Stage Breast Cancer
- Management of Breast Cancer in Pregnant Patients
Gastrointestinal Cancer
- Immunotherapy for Gastroesophageal Cancers
- Targeted Therapy for Biliary Cancers
- Systemic Therapy for Advanced Neuroendocrine Cancer
- Perioperative Management of Gastric Cancer
- Neoadjuvant and Adjuvant Therapy for Rectal Cancer, Including Watchful Waiting
Genitourinary Cancer
- Genomic and Germline Testing in Local and Advanced Prostate Cancer
- Genitourinary Cancers Survivorship
- Special Considerations for Elderly Patients with Genitourinary Cancers
- Endorsement of Appropriate Use Criteria for Imaging Evaluation of Biochemical Recurrence of Prostate Cancer After Definitive Primary Treatment
- Update: Systemic Therapy in Men with Metastatic Castration-Resistant Prostate Cancer
Gynecologic Cancer
- Relapsed Uterine
- Endorsement of ASTRO RT for Cervical Cancer
- First Platinum-Sensitive Ovarian Cancer Recurrence
- Gynecologic Survivorship
- Update: Neoadjuvant Chemotherapy for Ovarian Cancer
Head and Neck Cancer
- Use of Immune Checkpoint Inhibitors and PD-L1 Testing in Head and Neck Squamous Cell Carcinoma, Focusing on Recurrent/Metastatic Disease
- Transoral Robotic Surgery and Multidisciplinary Care of Oropharynx Cancer: Pre-op Decision-Making, Post-Op Treatment
- Consideration of Dental Care and Osteonecrosis in Patients Treated with Radiotherapy for Head and Neck Cancer
- Management of Locoregionally Recurrent Head and Neck Cancer Including Re-Irradiation
- Use of Systemic Treatment in the Management of Advanced Thyroid Cancer
Multi-Site
- Germline Genetic Testing
- Recommendations Regarding the Testing of Tumor-Agnostic Markers and Offering Associated Therapies
- Management of Leptomeningeal Disease
- Use of cfDNA in Diagnosis and Monitoring in Solid Tumors As Well As Lymphomas
Resource Stratified
- Update: Chemo- and Targeted Therapy for Patients with Triple-Negative, HER2+, or ER+ and Endocrine Resistant Metastatic Breast Cancer
- Update: Endocrine Therapy for ER+/PR+ Metastatic Breast Cancer
- Update: Survivorship Care in Adolescents, Young Adults, and Adults
- Update: Treatment of Patients with Endometrial Cancer
- Update: Geriatric Oncology
Supportive Care
- Prognostic Communication and Advance Care Planning
- Medical Cannabis in Cancer Symptom Care
- Integration of Palliative Care into Standard Oncology Care Update
- Management of Financial Toxicity of Cancer and its Treatment
- Management of Dermatologic Events to Cancer Therapies
Survivorship
- YA Survivorship for Ages 21-39
- Management of Sleep Problems in Cancer Survivors
- Exercise, Weight, and Obesity in Post-Treatment Cancer Survivors
- Survivorship After Stem Cell Transplantation
- Survivorship for Metastatic (Non-Hematological) Cancer
Thoracic
- Systemic Therapy for Resectable EGFR Positive NSCLC
- Systemic Therapy for Small Cell Lung Cancer
- Management of Oligometastasis and Oligoprogressive Disease
Recently Published Guidelines
- Chemotherapy in Combination with Radiotherapy for Definitive-intent Treatment of Stage II to IVA Nasopharyngeal Carcinoma
- Systemic Therapy for Advanced Hepatocellular Carcinoma
- Update: Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer
- Metastatic Carcinoma and Myeloma of the Femur
- PARP Inhibitors for Ovarian Cancer
- Update: Metastatic Pancreatic Cancer
- Update: Hepatitis B Virus Screening and Management for Patients with Cancer Prior to Therapy
- Update: Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers
- Update: Antiemetics
- Treatment of Locally Advanced Esophageal Carcinoma
- Management of Cancer Cachexia
- Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck
- Management of Hereditary Breast Cancer
- Systemic Therapy for Melanoma
- Treatment of Patients with Late-Stage Colorectal Resource-Stratified Guideline
- Management of Male Breast Cancer
- Therapy for Stage IV Non-Small Cell Lung Cancer without Driver Alterations
- Bone Health and Bone-targeted Therapies for Prostate Cancer
- Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer
- Optimum Imaging Strategies for Advanced Prostate Cancer
- Estrogen and Progesterone Receptor Testing in Breast Cancer
- Lung Cancer Surveillance After Definitive Curative-Intent Therapy
- Molecular Biomarkers in Localized Prostate Cancer
- Patient-Centered Standards for Medically Integrated Dispensing
- Management of Osteoporosis in Survivors of Adult Cancers with Nonmetastatic Disease
- Use of Endocrine Therapy for Breast Cancer Risk Reduction
- Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer
- Medication-Related Osteonecrosis of the Jaw
- Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision-Making for Early-Stage, Operable Breast Cancer
- Potentially Curable Pancreatic Adenocarcinoma
- Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: ASCO Clinical Practice Guideline Update—Integration of Results From TAILORx
- Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer
- Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer