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**Letters of Intent (LOI) are due August 31, 2020. Only approved LOIs will be invited for full application. Submission of full application is due on October 20, 2020.**

The Advanced Clinical Research Award (ACRA) is designed to support physician-scientists committed to performing original, clinical cancer research in an area not currently funded. This research must have a patient-oriented focus, including a clinical research study and/or translational research involving human subjects.

The ACRA in Immune Checkpoint Inhibitor Therapy is intended to support research to determine successful therapeutic combination regimens to overcome resistance problems associated with immune checkpoint inhibitors. The focus of this award is to understand 1) mechanisms of resistance to immune checkpoint inhibitors, 2) therapeutic approaches of combining immune checkpoint therapy with neoadjuvant strategies, 3) novel drug combination strategies with PD-1 inhibitors.

To download the Request for Proposals (RFP), click here.

Funding Available

The ACRA is a three-year grant totaling $450,000 that supports personnel and/or research expenses, and travel to attend the Conquer Cancer Grants and Awards Ceremony at the ASCO Annual Meeting. 

There is funding for one ACRA in Immune Checkpoint Inhibitor Therapy.


Applicants must meet the following criteria to qualify for an ACRA:

  • Be a physician (MD, DO, or international equivalent) working in any country
  • Be in the fourth to ninth year of a full-time, primary faculty appointment in a clinical department at an academic medical institution at the time of grant submission.
  • Have completed productive post-doctoral/post fellowship research and demonstrated the ability to undertake independent investigator-initiated clinical research.
  • Be an ASCO Full Member or have submitted a membership application with the grant application.
  • Be able to commit 75% of full-time effort in research (applies to total research, not just the proposed project) during the award period.

Application Instructions

All application materials must be in English and must be submitted through the Application Portal. Paper applications or applications sent by e-mail or fax will not be accepted.

Open: Apply by August 31, 2020.

Application Deadlines

Application Open: 

July 1, 2020

Letter of Intent Deadline: 

Application Deadline: 

August 31, 2020

Award Term: 

July 1, 2021 to June 30, 2024



This list reflects commitments as of July 1, 2020.

This grant receives support that may result in a report to the CMS Open Payments website under the Physician Payments Sunshine Act. The supporting companies are required to report the amount of the grant, the names of physicians who are awarded this grant, and the names of their institutions. This information may appear on the Open Payments websiteFind out more information about the Sunshine Act and CMS Open Payments program.