Listed below are the current guidelines, provisional clinical opinions, endorsements, and updates in development. Topics prioritized for development by the Clinical Practice Guidelines Committee and Guideline Advisory Groups are listed by disease site. To submit a topic for consideration, take our survey. To learn more about the ASCO Guideline development process, access the Guideline Methodology page.

Guidelines/Provisional Clinical Opinions (PCOs)/Endorsements in Development

Breast Cancer

Gastrointestinal Cancer

  • Adjuvant Therapy for Stage II Colon Cancer
  • Advanced Colon Cancer

Genitourinary Cancer

Head and Neck Cancer

  • Use of Immune Checkpoint Inhibitors and PD-L1 Testing in HNSCC

Neurooncology

  • ASCO-ASTRO-SNO Treatment of Patients with Brain Metastases
  • ASCO-SNO Therapy for Diffuse Astrocytic and Oligodendroglial Tumors

Resource Stratified

Supportive Care

  • Salivary Gland Hypofunction and/or Xerostomia Induced by Non-Surgical Cancer Therapies: ISOO/MASCC/ASCO Clinical Practice Guideline
  • Diet, Physical Activity, and Weight Management During Cancer Treatment
  • Use of Opioids During Cancer Treatment

Survivorship

Thoracic

  • Management of Stage III NSCLC

Multi-Site

  • Somatic Genomic Panel Testing for Metastatic Disease

Guideline Priorities 2021-2022

Breast Cancer

  • Adjuvant Endocrine Therapy with Hormone Receptor-Positive Breast Cancer
  • Postmastectomy Radiotherapy: American Society of Clinical Oncology, American Society of Radiation Oncology, and Society of Surgical Oncology Joint Guideline
  • Patient and Disease Characteristics and Recurrence Risk Recommendations (endorsement of Cancer Care Ontario guideline)
  • Sentinel Lymph Node Biopsy for Patients With Early-Stage Breast Cancer
  • Breast Cancer Follow-Up and Management After Primary Treatment/ACS-ASCO Breast Cancer Survivorship Care 

Gastrointestinal Cancer

  • Systemic Therapy for Well-Differentiated (Grade 1,2,3) Neuroendocrine Cancer
  • Neoadjuvant and Adjuvant Therapy for Rectal Cancer, Including Watchful Waiting
  • Perioperative Management of Gastric Cancer with Diagnostic Laparoscopy and Nodal Dissection and Pathology
  • Treatment Options for Anal Cancer
  • Treatment Options for Locoregional and Metastatic Small Bowel/Ampullary Cancer

Genitourinary Cancer

  • Adjuvant and Salvage Radiotherapy After Prostatectomy Endorsement
  • Primary Tumor-Directed and Metastasis-Directed Local Therapy in Oligometastatic Prostate Cancer 
  • Special Considerations for Elderly Patients with Genitourinary Cancers
  • Genitourinary Cancers Survivorship
  • Active Surveillance for the Management of Localized Prostate Cancer Endorsement

Gynecologic Cancer

  • Endorsement of ASTRO Radiation Therapy for Cervical Cancer guideline
  • Relapsed uterine cancer
  • First platinum-sensitive ovarian cancer recurrence
  • GYN Survivorship

Head and Neck Cancer

  • Transoral Robotic Surgery and Multidisciplinary Care of Oropharynx Cancer: Pre-op Decision-Making, Post-Op Treatment
  • Consideration of dental care and osteonecrosis in patients treated with radiotherapy for head and neck cancer
  • Use of systemic treatment in the management of advanced thyroid cancer
  • Management of locoregionally recurrent head and neck cancer including re-irradiation

Multi-Site

  • Use of cfDNA in diagnosis and monitoring in solid tumors as well as lymphomas
  • Endorsement of CAP MMR and MSI testing for immune checkpoint inhibitor therapy
  • Endorsement of ASTRO soft-tissue sarcoma guideline
  • Endorsement of CAP biomarker testing for glioma guideline
  • Management of Leptomeningeal Disease
  •  Advanced Thyroid Cancer 

Resource Stratified

  • Chemo- and Targeted Therapy for Patients with Triple-Negative, HER2+, or ER+ and Endocrine Resistant Metastatic Breast Cancer
  • Endocrine Therapy for ER+/PR+ Metastatic Breast Cancer
  • Survivorship Care in Adolescents, Young Adults, and Adults
  • Treatment of Patients with Endometrial Cancer
  • Geriatric Oncology

Supportive Care

  • Patient-Clinician Communication, adding discussion of financial toxicity, prognostic communication, and advance care planning
  • Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy
  • Management of Dermatologic Events from Cancer Therapies
  • Vaccinations, Including COVID, in the Setting of Hematologic Malignancy/HCT and Solid Cancers
  • Use of White Cell Growth Factors

Survivorship

  • Management of sleep problems in cancer survivors
  • Exercise – endorsement of ACSM guideline
  • Survivorship after SCT

Thoracic

  • Adjuvant Chemotherapy and Adjuvant Radiation Therapy for Stages I-IIIA Resectable Non-Small Cell Lung Cancer Update
  • Treatment of Malignant Pleural Mesothelioma Update
  • Management of multifocal lung adenocarcinoma
  • Duration of immune checkpoint therapy for stage IV Lung cancer
  • Management of typical and atypical carcinoid of the lung

Recently Published Guidelines