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  1. National Cancer Institute: SEER stat fact sheets: Melanoma of the Skin.
  2. Ribas A, Hamid O, Daud A, et al.: Association of pembrolizumab with tumor response and survival among patients with advanced melanoma. JAMA 315:1600-1609, 2016
  3. Topalian SL, Sznol M, McDermott DF, et al.: Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 32:1020-1030, 2014
  4. Schadendorf D, Hodi FS, Robert C, et al.: Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma. J Clin Oncol 33:1889-1894, 2015
  5. Postow M, Chesney J, Pavlick A, et al.: Initial report of overall survival rates from a randomized phase II trial evaluating the combination of nivolumab (NIVO) and ipilimumab (IPI) in patients with advanced melanoma (MEL). Presented at the 107th Annual Meeting of the American Association for Cancer Research, New Orleans, LA, April 16-20, 2016 (abstr CT002)
  6. Eggermont AM, Chiarion-Sileni V, Grob JJ, et al.: Prolonged survival in stage III melanoma with ipilimumab adjuvant therapy. N Engl J Med [epub ahead of print on October 7, 2016]
  7. WHO International Agency for Research on Cancer: GLOBOCAN 2012: Estimated cancer incidence, mortality and prevalence worldwide in 2012.
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  11. US Food and Drug Administration: Atezolizumab (TECENTRIQ).
  12. US Food and Drug Administration: Pembrolizumab (KEYTRUDA) checkpoint inhibitor.
  13. National Cancer Institute: SEER stat fact sheets: Bladder cancer.
  14. American Cancer Society: Bladder cancer.
  15. US Food and Drug Administration: FDA approves new, targeted treatment for bladder cancer.
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  17. Business Wire: Merck’s KEYNOTE-045 studying KEYTRUDA® (pembrolizumab) in advanced bladder cancer (urothelial cancer) meets primary endpoint and stops early. 80%99s-KEYNOTE-045-Studying-KEYTRUDA%C2% AE-pembrolizumab-Advanced-Bladder
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  20. National Cancer Institute: SEER stat fact sheets: Oral cavity and pharynx cancer.
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  22. US Food and Drug Administration: Nivolumab for SCCHN.
  23. National Cancer Institute: SEER stat fact sheets: Ovarian cancer.
  24. Hamanishi J, Mandai M, Ikeda T, et al.: Safety and antitumor activity of anti-PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer. J Clin Oncol 33:4015-4022, 2015
  25. National Cancer Institute: SEER stat fact sheets: Hodgkin lymphoma.
  26. US Food and Drug Administration: Nivolumab (Opdivo) for Hodgkin lymphoma.
  27. Roemer MG, Advani RH, Ligon AH, et al.: PD-L1 and PD-L2 genetic alterations define classical Hodgkin lymphoma and predict outcome. J Clin Oncol 34:2690-2697, 2016
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  34. Nghiem PT, Bhatia S, Lipson EJ, et al.: PD-1 blockade with pembrolizumab in advanced Merkel-cell carcinoma. N Engl J Med 374:2542-2552, 2016
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  37. Song H, Dicks E, Ramus SJ, et al.: Contribution of germline mutations in the RAD51B, RAD51C, and RAD51D genes to ovarian cancer in the population. J Clin Oncol 33:2901-2907, 2015
  38. Holter S, Borgida A, Dodd A, et al.: Germline BRCA mutations in a large clinic-based cohort of patients with pancreatic adenocarcinoma. J Clin Oncol 33:3124-3129, 2015
  39. Vasen H, Ibrahim I, Ponce CG, et al.: Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers. J Clin Oncol 34:2010-2019, 2016
  40. Yurgelun MB, Allen B, Kaldate RR, et al.: Identification of a variety of mutations in cancer predisposition genes in patients with suspected Lynch syndrome. Gastroenterology 149:604-613.e20, 2015
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  42. Fransen M, Karahalios A, Sharma N, et al.: Non-melanoma skin cancer in Australia. Med J Aust 197:565-568, 2012
  43. Guy GP Jr, Machlin SR, Ekwueme DU, et al.: Prevalence and costs of skin cancer treatment in the U.S., 2002-2006 and 2007-2011. Am J Prev Med 48: 183-187, 2015
  44. Chen AC, Martin AJ, Choy B, et al.: A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention. N Engl J Med 373:1618-1626, 2015
  45. Zorogastua K, Erwin D, Thelemaque L, et al.: Intrinsic factors of non-adherence to breast and cervical cancer screenings among Latinas. J Racial Ethn Health Disparities 3:658-666, 2016
  46. National Cancer Institute: SEER stat fact sheets: Acute myeloid leukemia (AML).
  47. Stone RM, Mandrekar S, Sanford BL, et al.: The multi-kinase inhibitor midostaurin (M) prolongs survival compared with placebo (P) in combination with daunorubicin (D)/cytarabine (C) induction (ind), high-dose C consolidation (consol), and as maintenance (maint) therapy in newly diagnosed acute myeloid leukemia (AML) patients (pts) age 18-60 with FLT3 mutations (muts): An international prospective randomized (rand) P-controlled double-blind trial (CALGB 10603/RATIFY [Alliance]). Blood 126:6, 2015.
  48. National Cancer Institute: SEER stat fact sheets: Acute lymphocytic leukemia (ALL).
  49. Kantarjian HM, DeAngelo DJ, Stelljes M, et al.: Inotuzumab ozogamicin versus standard therapy for acute lymphoblastic leukemia. N Engl J Med 375: 740-753, 2016
  50. Shaw AT, Gandhi L, Gadgeel S, et al.: Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: A single-group, multicentre, phase 2 trial. Lancet Oncol 17:234-242, 2016
  51. US Food and Drug Administration: FDA approves new oral therapy to treat ALK-positive lung cancer.
  52. Nokihara H, Kondo M, Kim YH, et al.: Alectinib (ALC) versus crizotinib (CRZ) in ALK-inhibitor naive ALK-positive non-small cell lung cancer (ALK+ NSCLC): Primary results from the J-ALEX study. J Clin Oncol 34, 2016 (suppl; abstr 9008)
  53. National Cancer Institute: SEER stat fact sheets: Myeloma.
  54. Palumbo A, Chanan-Khan AAA, Weisel K, et al.: Phase III randomized controlled study of daratumumab, bortezomib, and dexamethasone (DVd) versus bortezomib and dexamethasone (Vd) in patients (pts) with relapsed or refractory multiple myeloma (RRMM): CASTOR study. J Clin Oncol 34, 2016 (suppl; abstr LBA4)
  55. Cristofanilli M, Turner NC, Bondarenko I: Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): Final analysis of the multicentre, double-blind, phase 3 randomised controlled trial. Lancet Oncol 17:425-439, 2016
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  58. US Food and Drug Administration: Palbociclib (IBRANCE capsules).
  59. National Cancer Institute: SEER stat fact sheets: Kidney and renal pelvis cancer.
  60. Choueiri TK, Escudier B, Powles T, et al.: Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): Final results from a randomised, open-label, phase 3 trial. Lancet Oncol 17:917-927, 2016
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  62. Janowitz T, Welsh SJ, Zaki K, et al.: Adjuvant therapy in renal cell carcinoma-past, present, and future. Semin Oncol 40:482-491, 2013
  63. Ravaud A, Motzer RJ, Pandha HS, et al.: Adjuvant sunitinib in high-risk renal-cell carcinoma after nephrectomy. N Engl J Med 375:2246-2254, 2016
  64. Haas NB, Manola J, Uzzo RG, et al.: Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renalcell carcinoma (ECOG-ACRIN E2805): A double-blind, placebo-controlled, randomised, phase 3 trial. Lancet 387:2008-2016, 2016
  65. Moore KN, Martin LP, Seward SM, et al.: Preliminary single agent activity of IMGN853, a folate receptor alpha (FRα)–targeting antibody-drug conjugate (ADC), in platinum-resistant epithelial ovarian cancer (EOC) patients (pts): Phase I trial. J Clin Oncol 33, 2015 (suppl; abstr 5518)
  66. Buckner JC, Shaw EG, Pugh SL, et al.: Radiation plus procarbazine, CCNU, and vincristine in low-grade glioma. N Engl J Med 374:1344-1355, 2016
  67. Park JR, Kreissman SG, London SG, et al.: A phase III randomized clinical trial (RCT) of tandem myeloablative autologous stem cell transplant (ASCT) using peripheral blood stem cell (PBSC) as consolidation therapy for high-risk neuroblastoma (HR-NB): A Children’s Oncology Group (COG) study. J Clin Oncol 34, 2016 (suppl; abstr LBA3)
  68. Venook AP, Niedzwiecki D, Innocenti F, et al.: Impact of primary (1°) tumor location on overall survival (OS) and progression-free survival (PFS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB/SWOG 80405 (Alliance). J Clin Oncol 34, 2016 (suppl; abstr 3504)
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  71. National Cancer Institute: SEER stat fact sheets: Pancreas cancer.
  72. Neoptolemos JP, Palmer D, Ghaneh P, et al.: ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma. J Clin Oncol 34, 2016 (suppl; abstr LBA4006)
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  77. Pan H, Gray RG, Davies C, et al.: Predictors of recurrence during years 5-14 in 46,138 women with ER+ breast cancer allocated 5 years only of endocrine therapy (ET). J Clin Oncol 34, 2016 (suppl; abstr 505)
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