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Childhood Cancer Survivors’ Exposure to Chemotherapy, Radiation Does Not Increase Risk of Birth Defects in their Children

December 12, 2011

ALEXANDRIA, Va. - Summary of a study being published online December 12, 2011, in the Journal of Clinical Oncology finding children of childhood cancer survivors do not have an increased risk for birth defects – despite the fact that their parents received treatment with radiation and/or certain forms of chemotherapy that can damage the DNA of cancer cells and healthy cells alike. The findings provide reassurance to cancer survivors about the potential effects of their own treatment on their children, and help guide family planning.


Study Shows No Increased Risk of Breast Cancer for Non-Carriers in Families with BRCA Gene Mutation

October 31, 2011

ALEXANDRIA, Va.- Summary of a study being published online October 31, 2011, in the Journal of Clinical Oncology finding that close relatives of women who carry mutations in a BRCA gene – but who themselves do not have such genetic mutations – do not have an increased risk of developing breast cancer compared to relatives of women with breast cancer who do not have such mutations. These results run counter to a previous study showing a higher risk for these women, and suggest they may not need extra cancer screening and other preventive measures.


Study Shows Dramatic Rise in Incidence of Oral Cancer Type Linked to HPV

October 3, 2011

ALEXANDRIA, Va. - A new study of oropharyngeal cancer suggests that dramatic increases in U.S. incidence of the cancer and survival since 1984 can be attributed to infection with the human papillomavirus (HPV). Using samples collected from registries in three states, researchers showed that the proportion of oropharyngeal cancers - particularly among men - that tested positive for HPV increased significantly over time, from slightly more than 16 percent of such cancers diagnosed during the 1980s to more than 70 percent diagnosed during the 2000s.


ASCO Issues Updated Guideline on the Use of Antiemetic Agents to Prevent Vomiting and Nausea after Chemotherapy and Radiation

September 26, 2011

ALEXANDRIA, Va.- The American Society of Clinical Oncology (ASCO) today issued an update to its clinical practice guideline on the use of antiemetic medications to prevent vomiting and nausea resulting from treatment with chemotherapy and/or radiation. The new guideline includes comprehensive, stratified recommendations on the use of antiemetics during treatment with chemotherapy drugs that are classified as high, moderate, minimal and low risk for causing vomiting and nausea.


MRI Predicts Survival in Locally Advanced Rectal Cancer

August 29, 2011

ALEXANDRIA, Va. - A new study has shown that magnetic resonance imaging (MRI) used to evaluate responses to pre-surgery (neo-adjuvant) chemotherapy or radiation may predict survival among patients with advanced rectal cancer. The findings suggest that MRI-assessed tumor responses to neoadjuvant therapy can help physicians to better plan their patients' subsequent treatments.


ASCO Examines Impact of Health Care Reform on Cancer Care Disparities; Makes Recommendations for Closing Gaps

August 1, 2011

ALEXANDRIA, Va. –To help address serious racial and economic disparities in cancer prevention, diagnosis, and treatment in the United States, the American Society of Clinical Oncology (ASCO) today released a policy statement that outlines specific provisions of 2010 Patient Protection and Affordable Care Act that have the potential to reduce these disparities


ASCO Issues Provisional Clinical Opinion Recommending EGFR Mutation Testing Prior to Use of First-Line Targeted Drugs for Advanced Lung Cancer

April 8, 2011

ALEXANDRIA, Va. - The American Society of Clinical Oncology (ASCO) today issued a provisional clinical opinion (PCO) on the clinical use of epidermal growth factor receptor (EGFR) mutation testing to identify patients with advanced lung cancer who may benefit from targeted agents known as EGFR tyrosine kinase inhibitors.


Researchers Find Many Elderly Men Are Undergoing Unnecessary PSA Screenings

March 28, 2011

ALEXANDRIA, Va. - In this News Digest you will find a summary of study published online in the Journal of Clinical Oncology March 28 finding that men in their seventies had prostate cancer screening nearly twice as often as men in their early fifties, who are more likely to benefit from prostate cancer detection and treatment.


Surgical Technique Helps Adult Male Survivors of Childhood Cancer Regain Fertility

March 11, 2011

ALEXANDRIA, Va. - In this News Digest you will find a summary of a study being published online March 14 in the Journal of Clinical Oncology finding that a surgical technique was able to find viable sperm and allow fertility in many male childhood cancer survivors who received chemotherapy and were thought to be sterile


ASCO Issues Updated Guideline on the Role of Bone-Modifying Agents in the Prevention and Treatment of Bone Metastases in Patients with Metastatic Breast Cancer

February 22, 2011

The American Society of Clinical Oncology (ASCO) today issued an update to its clinical practice guideline on the use of bone-modifying agents, in particular, osteoclast inhibitors, to prevent and treat skeletal complications from bone metastases in patients with metastatic breast cancer. The new guideline includes recommendations on the use of a new drug option, denosumab (Xgeva), and addresses osteonecrosis of the jaw, an uncommon condition that may occur in association with bone-modifying agents.


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