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The Breast Cancer Symposium expanded in 2008 to a two-and-a-half-day multidisciplinary symposium in order to provide more feature presentations on the latest multidisciplinary research from selected theme-based translational, and clinical abstracts, as well as related educational sessions. This symposium provided clinically relevant, in-depth discussions of how and when to translate new findings into patient care and how to be more selective about breast cancer therapy.