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Determining issues of importance for patients with lung cancer: Results of a web-based study in 660 patients with lung cancer to enhance the content validity of quality of life (QL) instruments.

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Sub-category:
Quality-of-Life Management

Category:
Patient Care

Meeting:
2008 ASCO Annual Meeting

Abstract No:
20518

Citation:
J Clin Oncol 26: 2008 (May 20 suppl; abstr 20518)

Author(s):
B. J. Davis, R. J. Gralla, P. J. Hollen, J. A. Petersen, R. B. Montgomery

Abstract:

Background: Identifying key issues for patients with cancer is central to assessing QL and patient reported outcomes (PROs), which aids in evaluating effectiveness of treatment programs for those with the disease. The first aim of this study was to enhance the content validity for the PRO instrument, the LCSS, by enlarging the patient panel (originally 121) with an additional 660 patients. These data can also be useful for any QL or symptom scale as well as helping to ascertain that programs address the needs expressed by patients. Methods: We used the established patient base of the web-based NexCura patient information resource to survey registered patients with lung cancer. Demographic stratifications included: stage of disease (metastatic 27%, locally advanced 37%, NED 36%); gender (55% women); KPS (>80 = 46%, 70 = 28%, 60 = 16%); median age 62; NSCLC = 82%, SCLC = 18%; current treatment. 660 patients completed the anonymous web-conducted survey. Patients were asked to rank 20 issues on a 5-point scale assessing the importance of each item. Issues included general, lung-specific, psychosocial, spiritual and summative items. Results: The 9 highest ranked items are seen below; results are described by percent of patients choosing the top category (very important) and the top 2 rating categories of importance. Conclusions: Ratings by disease subsets (such as NED or M1 extent; by gender; by lung cancer type) were fairly similar to results found for the whole group, with the exception of the pain item being ranked second in those with stage IV extent. These results represent the largest survey of patient concerns in lung cancer and support using computer-assisted survey technology to assess such information in all malignancies to obtain patient input rapidly from large patient samples. These results give strong support for content validity for the LCSS and should be helpful in a variety of assessments in patients with lung cancer.

Very ImportantVery Important + Important
Good QL80%98%
Maintaining independence71%97%
Being a burden to others65%89%
Perform normal activities64%96%
Able to sleep63%94%
Having pain59%86%
Being fatigued58%93%
Having shortness of breath58%89%
Being depressed47%82%
Lower ranked items (not shown): sexuality, GU, and spiritual issues; other symptoms


Abstract Disclosures

Abstracts that were granted an exception in accordance with ASCO's Conflict of Interest Policy and are designated with a caret symbol (^) here and in the print version.


  Associated Presentation(s):

    

No items found.


  Other Abstracts in this Sub-Category:

    

1. A patient-level meta-analytic investigation of the prognostic significance of baseline quality of life (QOL) for overall survival (OS) among 3,704 patients participating in 24 North Central Cancer Treatment Group (NCCTG) and Mayo Clinic Cancer Center (MC) oncology clinical trials.

Meeting: 2008 ASCO Annual Meeting   Abstract No: 9515   First Author: A. D. TAN
Category: Patient Care - Quality-of-Life Management

    

2. An examination into quality of life as a prognostic survival indicator. Results of a meta-analysis of over 10,000 patients covering 30 EORTC clinical trials.

Meeting: 2008 ASCO Annual Meeting   Abstract No: 9516   First Author: C. Quinten
Category: Patient Care - Quality-of-Life Management

    

3. Electronic self-report assessment for cancer (ESRA-C): Results of a randomized clinical trial.

Meeting: 2008 ASCO Annual Meeting   Abstract No: 9519   First Author: D. L. Berry
Category: Patient Care - Quality-of-Life Management

    

More...


  Abstracts by B. J. Davis :

    

1. Determining issues of importance for patients with breast cancer: Results of a web-based study in 1,072 patients to enhance the content validity for the development of a new health-related quality of life (QL) instrument, the Breast Cancer Symptom Scale (BCSS).

Meeting: 2009 ASCO Annual Meeting   Abstract No: e20615   First Author: J. L. Horigan
Category: Patient Care - Quality-of-Life Management

    

2. Determining issues of importance for patients with lung cancer: Results of a web-based study in 660 patients with lung cancer to enhance the content validity of quality of life (QL) instruments.

Meeting: 2008 ASCO Annual Meeting   Abstract No: 20518   First Author: B. J. Davis
Category: Patient Care - Quality-of-Life Management

    

3. An exploration of factors important to men undertaking active surveillance for the management of low risk prostate cancer

Meeting: 2008 Genitourinary Cancers Symposium   Abstract No: 142   First Author: T. Pickles
Category: Genitourinary Cancers - Prostate

    

More...


  Presentations by B. J. Davis :

    

No items found.


  Educational Book Manuscripts by B. J. Davis :

    

No items found.




 
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