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Sub-category:
Epidemiology/Molecular Epidemiology
Category:
Tumor Biology and Human Genetics1
Meeting:
2005 ASCO Annual Meeting
Session Type and Session Title:
This abstract will not be presented at the 2005 ASCO Annual Meeting but has been published in conjunction with the meeting.
Abstract No:
9636
Citation:
Journal of Clinical Oncology, 2005 ASCO Annual Meeting Proceedings. Vol 23, No. 16S, Part I of II (June 1 Supplement), 2005: 9636
Author(s):
S. F. Husain, W. Morzycki, R. Dewar, D. Rayson
Abstract:
Background: This study was conducted to evaluate the incidence and survival rates for mesothelioma in the province of Nova Scotia (NS), Canada using population-based data. Methods: A retrospective chart review was performed, using NS cancer registry data and cancer centre patient charts of all documented cases of mesothelioma in the province of NS between 1990 and 2002. Results: Between 1990 and 2002, 101 cases of mesothelioma were recorded. The overall incidence of mesothelioma was 1.3 per 100,000. The incidence rate by gender showed a higher rate in men than women with 1.47 per 100,000 versus 0.2 per 100,000, respectively. Incidence rates were highest in the area of Halifax County. The median age at the time of diagnosis was 70 in men and 64 in women. The distribution of mesothelioma per anatomical site was 87% pleural, 12% peritoneal and 1% unspecified. The most common presenting symptoms were shortness of breath (61%), chest pain (43%), and cough (27%). 69% of patients had documented asbestos exposure and 78% had a positive smoking history. The two year overall survival rate was 10% (10% for men and 15% for women). Conclusions: In Nova Scotia, Canada, the highest incidence of mesothelioma occurred in geographic areas where shipyards were common (Halifax County). Pleural disease was the most common anatomical site of origin for both genders. Men were at higher risk compared to women for the development of pleural mesothelioma over the time interval studied. Variable rates of mesothelioma were observed during the period examined.
 Associated Presentation(s):
Other Abstracts in this Sub-Category:
Abstracts by S. F. Husain:
Presentations by S. F. Husain:
Educational Book Manuscripts by S. F. Husain:
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